Synthesis of the eight enantiomerically pure diastereomers of the 12-F(2)-isoprostanes.
نویسندگان
چکیده
Syntheses of the eight enantiomerically pure diastereomers of the 12-F(2)-isoprostanes (4-11) are described. The key steps included rhodium-mediated intramolecular cyclopropanation and enzymatic resolution of the racemic diol 12.
منابع مشابه
A potential route to neuroprostanes and isoprostanes: preparation of the four enantiomerically pure diastereomers of 13-F4t-neuroP.
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عنوان ژورنال:
- Journal of the American Chemical Society
دوره 124 44 شماره
صفحات -
تاریخ انتشار 2002